FARCOCIN CREAM-Egypt

Pharco Corporation

Pharmacological Action:

Farcocin cream and Farcocin ointment (gentamicin) are highly effective formulations for topical treatment of primary and secondary skin mfections caused by gentamicin-sensitive pathogenic bactena. Farcocin is bactericidal against most strains of staphylococci (including penicillin-resistant strams), some strains 01 streptococci and the Gram-negative bacteria: Pseudomonas aerugmosa (insensitive to many antibiotics). Escherichia coli and klebsiella, Proteus, Enterobacter, Citrobacter
and Serratia species. Gentamicin (an aminoglycoside antibiotic) binds irreversibly to tle 30S ribosomal subunits causing inhibition of bacterial protein synthesis and induces misreac.mg of the genetic code with eventual bacterial cell death. Farcocin is formulated in cream and 0 ntment forms to suit the different coromons of infected skin. The cream suits hairy and intertrigmous areas and is recommended for wet oozing and greasy infected skin while the ointment IS preferable for infections
of dry eczematous or psoriatic skin.

Pharmacokinetics:

Systemic absorption of gentamicin has been reported after topical use on denuded skin and burns and following instillation into the imgation of wounds.

Indications:

Skin infections caused by gentamicin-susceptible bacteria including :
Primary skin infections: Impetigo contagiosa, furunculosis, ecthyma, superficial folliculitis, sycosis barbae and pyoderma gangrenosum .
Secondary skin infections: infected wounds and skin ulcers, infected superficial burns, infectious eczematoid dermatitis, Infected seborrheic and contact derrnatitrs, pustular acne, pustular psoriasis, infected insect bites and stings, paronychia and bacterial supennfection.